Mini Duo Bottles and Packaging
Mini Duo Package
Mini Duo Bottles
Vitamin C Swatch
Enzyme Active Retinol Swatch

Mini Molecular Super Duo

Rated 4.9 out of 5
Based on 310 reviews
  • The two cult-favorite serums, mini-sized
  • For smoothness, brightness, clarity and evenness
  • Guaranteed improvements in 30 days
  • Lab-made batch, ready to ship
Regular price$80.00
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2-Step Line | 30 days

By popular demand, this two-serum gift set contains our award-winning, cult-favorite serums in extremely small and cute 30-day travel (or gift) sizes.

Enzyme-Active Retinol Serum  
For skin smoothing and clarifying

Vitamin C Superserum 
For boosting brightness and evenness

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Mini Molecular Super Duo

Regular price$80.00 / 2-Step Line | 30 days

Youthful, more even and glowy-looking skin in 30 days.

Enzyme-Active Retinol Serum

Grooming Awards Winner for "Best Retinol" and Coveteur Editors' Choice,this serum successfully captures (for the first time) nature's most powerful and gentle renewing molecule.

Indicated for: Boosting natural collagen and modulating skin cell behavior to fill in wrinkles, stop new ones from forming and restoring a smoother, more youthful complexion

Vitamin C Superserum

Listed on Vogue's Best Vitamin Cs list and TheZoeReport's "best kept secret in the industry", this serum will reinvent your idea of how Vitamin C should look, feel and WORK. Contains the most effective topical antioxidant on Earth: 10% L-ascorbic acid.

Indicated for: Defending against environmental stressors to fade dark spots, even out complexion and brighten dull skin.

Our clients don't hold back

★★★★★

I absolutely love your products!! They’ve completely transformed my skin over a 5 week period. Just ordered my second bottles of the Vitamin C serum and Retinol. These products are worth every penny and I wish they would receive more hype because they deserve it!

Jessica B.

Verified Buyer

★★★★★

My new favorite products!
In love with all of the products! Have gone through 2 bottles of retinol and the vitamin c serum. I can see a change in my skin and have used all sort of products that were quadruple the price. This is the only one that I can truly say that I could feel and SEE the difference!

Eileen I.

Verified Buyer

★★★★★

Excellent products.
I’ve noticed my skin is very vibrant and wrinkle free. I’m in my early 30s and this has helped with smoothing and reducing my wrinkles. I’ve also noticed it’s helped with acne scars that I’ve had for years. Highly recommend for daily use.

Matthew H.

Verified Buyer

★★★★★

This is undoubtedly the best skincare I’ve ever used. My skin is glowing after just the first day.

Victoria B.

Verified Buyer

★★★★★

I’m obsessed with this skincare line! I have sensitive/combination skin and these products have transformed my face. My skin looks HEALTHY! I am so impressed with both serums…just wow. I highly recommend!!

Briana C.

Verified Buyer

★★★★★

My skin has never looked better and it's a third the retail cost of what I had been using.

Anna B.

Verified Buyer

★★★★★

Great Retinol Serum!
I really like this retinol serum. The way it is packaged makes you feel like it is delivered, and will stay, fresh so that all the benefits can be achieved! I noticed a definite improvement in my dark spots and skin seems bright. Use it in combination with the C-Serum. Wil buy again for sure!

Jules T.

Verified Buyer

★★★★★

WOW! Molecular skin-bliss!

Marco M.

Verified Buyer

★★★★★

I am a product junkie and love trying new things. However, this skin care line is so good, I am hooked! I imagine I will be a customer for life.

Nancy G.

Verified Buyer

space-age packaging technology
Potency maximized

A patented bottling method, for next-level ingredient potency.

L-Ascorbic Acid and Enzyme-Active Retinol are EXTREMELY sensitive to any oxygen or light exposure. That's why most Vitamin C serums on the market will appear brown and smell like BBQ...because it's oxygen-spoiled.

Our lab bottles the serums in a completely oxygen and UV-free environment giving you the purest most effective ingredients on the market.

What to expect in 30 days?

Smoother, more glowing, even and youthful-looking skin.

We say 30 days as a formality. Over half of our clients see complexion improvements within the first 7 days. It's shocking what happens when you just follow the dermatological science with complete precision. See our FAQ for a detailed list of the peer-reviewed, academic research behind the line.

Paraben free. USA lab-made. and obviously no animal testing.

average rating 4.9 out of 5
Based on 310 reviews
  • 5 Stars
    276 Reviews
  • 4 Stars
    28 Reviews
  • 3 Stars
    2 Reviews
  • 2 Stars
    4 Reviews
  • 1 Star
    0 Reviews
97% of reviewers would recommend this product to a friend
Customer photos and videos
310 Reviews
Reviewed by Erika
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

CLEAN, PRISTINE, & INTELLIGENT SKINCARE

I cant even express to you how much I’ve battled with hormonal cystic acne, dark hyperpigmentation, dry, and oily skin. I’ve spent thousands on peels, creams, serums, pills, and countless sad evenings researching ingredients and how they can alter your skin and gut microbiome. Through the years I’ve had to learn the hard way how paramount clean and well preserved ingredients are. After 13 years of an arduous journey- I’ve landed, with confidence, on Protocol. As we all know, Vitamin C is a cute but unstable monster, retinol is an irritating acid at certain percentages, HA is tricky without the right moisture/reactive combination but Protocol has mastered all of it with scientific sophistication. Aside from its CLEAN (non carcinogenic, paraben free, hormone-disrupter free) ingredients, the packages are ingenious (check out their page on the way no light or air penetrate the serums). Also, their customer care is the sweetest, most understanding, and most responsive I’ve dealt with.

Listen, I don’t usually freak like this over a brand but I’m telling you it will change your life and simplify your complicated skin routine. I look younger, I look fresher, I look brighter, and I feel like I can just take a breath and trust this brand. You owe it to yourself to try this. My skin made me sad for so long and with this I’m getting my confidence back every day.

XX

Erika

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Reviewed by Kimberly
Verified Reviewer
I recommend this product
Age
35 - 44
Skin Type
Combination
Skin Concerns
  • Acne
  • Age Defense
  • Dark Spots
  • Pores
My Results
  • Brighter Complexion
  • Glowing Skin
  • More Even Tone
  • Reduced Sun Spots/Discoloration
Rated 5 out of 5
Review posted

My 10 year old acne scars literally fell off my face

I thought I was imagining it at first but 3 weeks in my whole family was commenting on how good my skin looked and asking what I was doing. I took before pic a few days in because it already seemed to be changing so quickly. The after pics are from my 2nd round of the complete line and the improvement is REAL. I'm shook. THANK YOU PROTOCOL!!

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Reviewed by Kate
I recommend this product
Rated 5 out of 5
Review posted

I can't believe it

This is unbelievable. I'm 32. I've been using retinol products and "Retin-'A'" 0.05 for about 6 years. I microneedle and get red light therapy. This is the best retinol I have ever used. I've seen more results from one week of use than I have from months of "Retin-'A'". I can also use it every night without drying which is insane. I'll report back in 6 months but this is not a drill. It is. The best.

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Reviewed by Kirby O.
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Fan for life.

I've had issues with my skin for the past two or so years, I think because of damage done to my skin barrier from using Biologique Recherche p50, and then other chemical exfoliants. My skin was very, very angry with me, and I responded with panic and more products. Wrong. I finally gave my skin some space to breath (thank you stay-at-home orders), and didn't put anything besides sunscreen on for two weeks - highly recommend. The first products I used again were Protocol and Avène Cicalfate+ Restorative Protective Cream (so good for sensitive skin), and my skin has never looked better. Like ever.

I have never seen these types of results, yet alone this quickly (about three months with Retinol/Vit C/Moisturizer). I use the Retinol every second or third night so I don't have bitchy skin deja-vu. The cleanser is magic, truly. So worth it. I just started using it, and every other night works best so far. I think I started out putting too much of the moisturizer on (I feel like this might have been part of my problem all along), but now that I take more time to apply instead of just slapping it on I am much happier with how my skin really absorbs the product. I use it during the daytime, and Cicalfate at night. My skin is completely different now - blemish free, less redness, super plump and strong, and I worry far less about it (the best part).

Protocol's customer service is also fantastic in general, they get that it's 2020 and they're a skincare brand. Thank you!!

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Reviewed by Sarah G.
Verified Buyer
I recommend this product
Age
35 - 44
Skin Type
Combination
Skin Concerns
  • Acne
  • Age Defense
  • Dark Spots
  • Dullness
  • Pores
My Results
  • Glowing Skin
  • Smoother Skin
  • Firm & Lifted Skin
  • Skin Radiance
  • Softer Skin
Rated 5 out of 5
Review posted

Amazing Results!

My 43 year old stressed acneic aging skin has never looked better! The protocol line of products has brought new life to my problem skin. I feel such a sense of rejuvenation since using this line! My skin is softer, more supple, and brighter. I also see fewer fine lines and acne scars!

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