Skin Molecule Optimization Line (SMOL)
Skin Molecule Optimization Line (SMOL)
Skin Molecule Optimization Line (SMOL)
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Ideal for new clients

Skin Molecule Optimization Line (SMOL)

Rated 4.9 out of 5
Based on 525 reviews
  • The award-winning routine in a mini, 30-day supply
  • For rapid skin-smoothing, clarifying and glow-boosting
  • Visible results guaranteed in 30 days
  • Lab-made batch, ready to ship
Regular price$132.00
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4-Step Line | 30 days

Lab Summary:
The game-changing Dream Team of skin-renewing molecules that were impossibly packed into Protocol’s critically-acclaimed, four-step Complete Renewing Line, now completely reimagined in adorable, 30-day dosages. They’re miniature and mighty. Skin-transforming and so, so smol.

Which super-advanced renewing molecules are captured in the SMOL set?

– The rarest, gentlest and most powerful "Unicorn of Retinoids", (the naturally-occurring enzyme-active form "retinal").
– The Queen Bee of antioxidants, (L–ascorbic acid, pH 3.46).
– Mother Nature's most dedicated moisturizing trio, (niacinamide, hyaluronic acid and glycerin).
– The Annie Oakley of resurfacing exfoliants, (glycolic acid and lactic acid AHAs).

Limited SMOL sets ship directly from the lab.

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We're not guessing about results.

The Journal of Cosmetic Dermatology concluded that ingredients used in the SMOL Renewing Line were proven to be more effective than a $3,000 Glycolic Acid Chemical Peel applied by a Dermatologist at reducing visible signs of aging like wrinkles and fine lines.

- C. Rouvrais. Journal of Cosmetic Dermatology 2018 Dec 17


The Anatomy of Molecular Renewing Power

Protocol Skincare SMOL Skin Molecule Optimization Line Mini Serums
A patented bottling method, for next-level ingredient potency

L-Ascorbic Acid and Enzyme-Active Retinol are EXTREMELY sensitive to any oxygen or light exposure. That's why most Vitamin C serums on the market will appear brown and smell like BBQ...because it's oxygen-spoiled. Our lab bottles the serums in a completely oxygen and UV-free environment giving you the purest most effective ingredients on the market.

What to expect in 30 days?
Smoother, more glowing, even and youthful-looking skin

We say 30 days as a formality. Over half of our clients see complexion improvements within the first 7 days. It's shocking what happens when you just follow the dermatological science with complete precision.

See our FAQ for a detailed list of the peer-reviewed, academic research behind the line.

Paraben free. USA lab-made. and obviously no animal testing.

Protocol Skincare Skin Molecule Optimization Line Skin

Don't take our word for it

★★★★★

I pride myself on staying abreast of skin care advancements. This line is GREAT. The best I’ve tried. ✌🏼❤️

Pepper G.

Verified Buyer

★★★★★

Skin Care Game Changer! Absolutely love all the the products. I can see a big difference in just 2 weeks of consistence routine use. My skin is brighter and smoother than ever. I'm 63 yrs old and everyone says I look twenty yrs younger! Good skin care makes it all possible. Thank you.

Veronica P.

Verified Buyer

★★★★★

Love this line! Okay- I’ve tried a few complete lines prior to taking the plunge with Protocol. One prescription-based and one other P brand that claims to be personalized. After about a year of not seeing the results I was hoping for I impulsively sprung for the SMOL line to give it a try. I have never received so many compliments on my skin since using this line religiously for a month. Dark spots are fading, my skin looks smooth and soft. I didn’t struggle with acne before so I can’t speak to it’s effect on that, but I have noticed fewer clogged pores and dry spots. No peeling or irritation and my skin feels hydrated and happy. 10/10 would recommend!

Pinkee E.

Verified Buyer

★★★★★

Great way to try the whole line!
I had been on the fence about trying Protocol for a while, and I’m so glad that I finally did. The small bottles were a great way to try the whole product line without breaking the bank. I have had no skin sensitivity to the products, and my skin appears overall brighter and my complexion is smoother after just 3 weeks. I will definitely purchase the big bottles next!

Meredith L.

Verified Buyer

★★★★★

Blown Away. I’m obsessed with this skincare line! I have sensitive/combination skin and these products have transformed my face. My skin looks HEALTHY! I am so impressed with both serums…just wow. I highly recommend!!

Brianna C.

Verified Buyer

★★★★★

I love that this set is packaged in a perfect 30-day dose — it feels like setting aside a full month to take extra-good care of me and my skin. I especially love the naicinamide and hyaluronic acid moisturizer; it soaks right in and moisturizes deeply. It’s so good and it’s my favorite product from this line-up!

Alice

Verified Buyer

★★★★★

Absolutely, positively love love love. Several reasons. 1. It's easy, 4 products not 3000. 2. Feels pure, simple, no crazy fragrance. 3. results, using about 3 weeks, I'm 64, not general good skin care in past. My skin is hydrated and fine lines, leathery dry skin gone. 4. Okay maybe silly, but I love packaging, it's simple, feels a little vintage.

Nancy J.

Verified Buyer

★★★★★

Excellent products. I learned about Protocol from a chemist and packaging expert. The way in which these products are packaged is just as important as what they contain. Both are top notch and I will order again.

Stephanie S.

Verified Buyer

★★★★★

I love the moisturizer, I am 68 years young and just coming off chemo and radiation treatments which is so hard on your skin. I have been using Protocol for just over 3 weeks and really can tell a difference.

Connie L.

Verified Buyer

average rating 4.9 out of 5
Based on 525 reviews
  • 5 Stars
    466 Reviews
  • 4 Stars
    47 Reviews
  • 3 Stars
    7 Reviews
  • 2 Stars
    5 Reviews
  • 1 Star
    0 Reviews
98% of reviewers would recommend this product to a friend
Customer photos and videos
525 Reviews
Reviewed by Erika
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

CLEAN, PRISTINE, & INTELLIGENT SKINCARE

I cant even express to you how much I’ve battled with hormonal cystic acne, dark hyperpigmentation, dry, and oily skin. I’ve spent thousands on peels, creams, serums, pills, and countless sad evenings researching ingredients and how they can alter your skin and gut microbiome. Through the years I’ve had to learn the hard way how paramount clean and well preserved ingredients are. After 13 years of an arduous journey- I’ve landed, with confidence, on Protocol. As we all know, Vitamin C is a cute but unstable monster, retinol is an irritating acid at certain percentages, HA is tricky without the right moisture/reactive combination but Protocol has mastered all of it with scientific sophistication. Aside from its CLEAN (non carcinogenic, paraben free, hormone-disrupter free) ingredients, the packages are ingenious (check out their page on the way no light or air penetrate the serums). Also, their customer care is the sweetest, most understanding, and most responsive I’ve dealt with.

Listen, I don’t usually freak like this over a brand but I’m telling you it will change your life and simplify your complicated skin routine. I look younger, I look fresher, I look brighter, and I feel like I can just take a breath and trust this brand. You owe it to yourself to try this. My skin made me sad for so long and with this I’m getting my confidence back every day.

XX

Erika

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Reviewed by Kimberly
Verified Reviewer
I recommend this product
Age
35 - 44
Skin Type
Combination
Skin Concerns
  • Acne
  • Age Defense
  • Dark Spots
  • Pores
My Results
  • Brighter Complexion
  • Glowing Skin
  • More Even Tone
  • Reduced Sun Spots/Discoloration
Rated 5 out of 5
Review posted

My 10 year old acne scars literally fell off my face

I thought I was imagining it at first but 3 weeks in my whole family was commenting on how good my skin looked and asking what I was doing. I took before pic a few days in because it already seemed to be changing so quickly. The after pics are from my 2nd round of the complete line and the improvement is REAL. I'm shook. THANK YOU PROTOCOL!!

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Reviewed by Kate
I recommend this product
Rated 5 out of 5
Review posted

I can't believe it

This is unbelievable. I'm 32. I've been using retinol products and "Retin-'A'" 0.05 for about 6 years. I microneedle and get red light therapy. This is the best retinol I have ever used. I've seen more results from one week of use than I have from months of "Retin-'A'". I can also use it every night without drying which is insane. I'll report back in 6 months but this is not a drill. It is. The best.

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Reviewed by Kirby O.
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Fan for life.

I've had issues with my skin for the past two or so years, I think because of damage done to my skin barrier from using Biologique Recherche p50, and then other chemical exfoliants. My skin was very, very angry with me, and I responded with panic and more products. Wrong. I finally gave my skin some space to breath (thank you stay-at-home orders), and didn't put anything besides sunscreen on for two weeks - highly recommend. The first products I used again were Protocol and Avène Cicalfate+ Restorative Protective Cream (so good for sensitive skin), and my skin has never looked better. Like ever.

I have never seen these types of results, yet alone this quickly (about three months with Retinol/Vit C/Moisturizer). I use the Retinol every second or third night so I don't have bitchy skin deja-vu. The cleanser is magic, truly. So worth it. I just started using it, and every other night works best so far. I think I started out putting too much of the moisturizer on (I feel like this might have been part of my problem all along), but now that I take more time to apply instead of just slapping it on I am much happier with how my skin really absorbs the product. I use it during the daytime, and Cicalfate at night. My skin is completely different now - blemish free, less redness, super plump and strong, and I worry far less about it (the best part).

Protocol's customer service is also fantastic in general, they get that it's 2020 and they're a skincare brand. Thank you!!

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Reviewed by Victoria B.
Verified Reviewer
I recommend this product
Age
55+
Skin Type
Combination
Skin Concerns
  • Age Defense
  • Dryness
  • Dullness
  • Pores
  • Wrinkles & Fine Lines
My Results
  • Healthy Skin
  • Glowing Skin
  • Smoother Skin
  • Softer Skin
  • Skin Radiance
Rated 5 out of 5
Review posted

Unbelievable!!!

I am 63 and I’m a skin care junkie. I have bought & used low & high end products. I bought the set and used it just today and the results are remarkable! I know immediately if something is good, bad or ok. This is undoubtedly the best skincare I’ve ever used. My skin is glowing after just the first day. I’m a forever customer. Ty so much for your products ❤️❤️❤️❤️

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